Infantile pyknocytosis, a rare cause of hemolytic anemia in newborns: report of two cases in twin girls and literature overview
نویسندگان
چکیده
Infantile pyknocytosis is a rare cause of neonatal jaundice and hemolytic anemia. We report on two cases in twin girls that were diagnosed on peripheral blood smear reading. Pyknocytosis should be considered in cases of early unexplained severe hemolytic anemia, and systematic peripheral smear review performed. Its management consists of phototherapy and RBC transfusion.
منابع مشابه
Neonatal pyknocytosis in a preterm dizygotic twin
Infantile pyknocytosis (IP) is a rare, self-limited neonatal haemolytic anaemia that may require multiple blood transfusions. Only a little more than 50 cases have been reported in the medical literature, and the great majority of them concerns term infants. The etiology of IP is not well understood; most likely it results from a transient extra-corpuscular factor, whose nature is unknown, tran...
متن کاملA Fetal Hemolytic Anemia in a Child with Cytomegalovirus Infection
Background Autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. Most of the cases are associated with viral or bacterial infections. In some cases, AIHA can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. Case report Especially in children younger...
متن کاملInfantile and Maternal Choriocarcinoma: A Case Report and Review of Literature
Background: Choriocarcinoma is a rare highly malignant trophoblastic neoplasm. It can be preceded by any form of gestation including a complete or a partial mole, miscarriage and normal pregnancy. Simultaneous intraplacental choriocarcinoma involving both mother and infant is extremely rare. Hepatomegaly, anemia, elevated ßHCG is the diagnostic triad. Here we report a 6 weeks old Afghan girl in...
متن کاملReport of two unrelated cases of Familial Thrombotic Thrombocytopeic Purpura
Thrombotic Thrombocytopenic Purpura (TTP) is a rare microangiopathic disorder characterised by the pentad of microangiopathic hemolytic anemia, thrombocytopenic purpura, neurologic abnormalities, fever, and renal disease. Decreased production and/or activity of ADAMTS13 is the cause of this disorder. ADAMTS13 is a metalloproteinase which is responsible of the cleavage of high weight multimers o...
متن کاملA case report with high bilirubinemia and hemolytic anemia during leptospirosis and a short review of similar cases
Background: Leptospirosis is characterized by very diverse clinical manifestations, which may range from flu-like subclinical forms to very severe presentations characterized by multi-organ failure, or to atypical presentations. One of its most aggressive presentations is Weil’s disease, characterized by jaundice, hemorrhagic phenomena and renal failure. Cases with high bilirubinemia over 30mg/...
متن کامل